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Deletion of Chromosomal Region 8p21 Confers Resistance to Bortezomib and Is Associated with Upregulated Decoy TRAIL Receptor Expression in Patients with Multiple Myeloma.

PLoS One · 2015 · PMC4574561 · PMID 26378933

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While a similar trend of TRAIL-R4 upregulation was observed in patients with del(8)(p21), this did not reach statistical significance possibly due to the use of a smaller sample size for flow cytometric phenotyping.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.