Inhaled Long-Acting β2-Agonists Do Not Increase Fatal Cardiovascular Adverse Events in COPD: A Meta-Analysis.

PLoS One · 2015 · PMC4574772 · PMID 26378450

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did not reach statistical significanceno p-value reported

One retrospective case-control study found that inhaled LABAs decreased all-cause mortality in COPD (OR 0.92, 95% CI 0.88 to 0.96) and that there was a trend toward a benefit in terms of cardiovascular deaths (OR 0.97, 95% CI 0.84 to 1.11), although this effect did not reach statistical significance [ 54 ].

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