Effects of dextromethorphan and oxycodone on treatment of neuropathic pain in mice.

J Biomed Sci · 2015 · PMC4578273 · PMID 26391752

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Furthermore, co-administration of DM with oxycodone showed better effects than oxycodone alone in suppressing the SNL-induced activation of astrocytes and microglia in the dorsal horn of spinal cord and also showed a trend to enhance the effect of oxycodone on decreasing the plasma level of proinflammatory cytokines.

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