Plasmodium Infection Is Associated with Impaired Hepatic Dimethylarginine Dimethylaminohydrolase Activity and Disruption of Nitric Oxide Synthase Inhibitor/Substrate Homeostasis.

We also calculated the correlation between hepatic DDAH activity and plasma ADMA/Arginine ratio in mice, and found a negative trend, i.e., mice with lower DDAH activity tended to have higher ADMA/Arginine ratios in plasma (r part = -0.23, p = 0.09; S4 Fig and S1 Table ).

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