Synthesis and Antiplasmodial Evaluation of Analogues Based on the Tricyclic Core of Thiaplakortones A-D.

Mar Drugs · 2015 · PMC4584354 · PMID 26389920

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a clear trendno p-value reported

16 ) a clear trend was observed, with the thiazine regiochemistry present in 12 , 14 and 16 conveying reduced cytotoxicity ranging from 1.6- to 13.6-fold.

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