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A RANKL mutant used as an inter-species vaccine for efficient immunotherapy of osteoporosis.

Sci Rep · 2015 · PMC4585926 · PMID 26412210

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showed a trendno p-value reported
Patients who developed anti-TNF antibodies showed a trend toward clinical improvement.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.