Initiation of Antiretroviral Therapy (ART) at Different Stages of HIV-1 Disease Is Not Associated with the Proportion of Exhausted CD8+ T Cells.

Interestingly, individuals with ART initiation before seroconversion were the only group with a five-parameter HIV-1-specific cytokine response that included IL-2 ( Fig 3A ), although this result did not reach statistical significance ( Fig 3B ).

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