Ventromedial prefrontal cortex drives hippocampal theta oscillations induced by mismatch computations.

We found marginally significant differences in the anterior hippocampal theta (peaking at x , y , z = − 18, − 10, − 12, p < 0.055 FWE-corrected) for the mismatch versus predictable ( Fig. 2 A) and for the mismatch versus unpredictable ( Fig. 2 B, peaking at x , y , z = − 30, − 22, − 24, p < 0.029 FWE-corrected) conditions.

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Second, in the iEEG study, while the amplitude of hippocampal theta on unpredictable trials fell between that observed for predictable and mismatch trials, this effect did not reach statistical significance.

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