Several detectable mediators, such as LTB 4 and PGE 2 , various HETEs [11-HETE, 15(S)-HETE, 18-HETE], and DHETs, the diol metabolites of EETs, showed a trend for reduced levels, which, however, did not reach statistical significance.
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Adipose triglyceride lipase acts on neutrophil lipid droplets to regulate substrate availability for lipid mediator synthesis.
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