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Functional characterization of biodegradable nanoparticles as antigen delivery system.

J Exp Clin Cancer Res · 2015 · PMC4596393 · PMID 26444005

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a marked trendno p-value reported
Indeed, PLGA-Rhod/PEI NPs showed a marked trend to aggregation with a massive cellular internalization associated with a clear pattern of cellular clustering.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.