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Interleukin-1 Antagonist Anakinra in Amyotrophic Lateral Sclerosis--A Pilot Study.

PLoS One · 2015 · PMC4596620 · PMID 26444282

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However, reduction of inflammatory cytokines like IL–6 and TNF did not reach statistical significance after six months of treatment.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.