Short-Term, High-Dose Fish Oil Supplementation Increases the Production of Omega-3 Fatty Acid-Derived Mediators in Patients With Peripheral Artery Disease (the OMEGA-PAD I Trial).

Although these trends did not reach statistical significance, levels of 10,17-diHDHA were significantly higher in the fish oil group compared with the placebo group after 1 month of treatment ( Figure 3 ) despite no significant differences between the 2 groups at baseline.

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