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Mice lacking GPR3 receptors display late-onset obese phenotype due to impaired thermogenic function in brown adipose tissue.

Sci Rep · 2015 · PMC4601089 · PMID 26455425

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Additionally, GPR3 KO mice tended to have lower sensitivity to insulin, although this did not reach statistical significance (ITT; Fig. 1G , right panel).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.