Efficacy of implantable cardioconverter defibrillator or cardiac resynchronization therapy compared with combined therapy in survival of patients with heart failure: a meta-analysis.

Although both meta-analyses found higher risk of all-cause death in CRT alone or ICD alone than CRT–ICD, results by Lam and Owen did not reach statistical significance (combined therapy vs CRT 0.85 [0.60–.22], combined therapy vs ICD 0.82 [0.57–1.18]).

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