Combination Low-Dose Tissue-Type Plasminogen Activator Plus Annexin A2 for Improving Thrombolytic Stroke Therapy.

Front Cell Neurosci · 2015 · PMC4604305 · PMID 26528130

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did not reach statistical significanceno p-value reported

Our experimental results showed the combination slightly reduced brain infarction compared to saline (9.2% reduction), and tPA (7.4% reduction) at 24 h after stroke, although the reductions did not reach statistical significance, whereas the combination significantly reduced (22.2% reduction, P < 0.05) the conventional tPA-elevated ICH transformation.

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