Expression Quantitative Trait Loci Information Improves Predictive Modeling of Disease Relevance of Non-Coding Genetic Variation.

PLoS One · 2015 · PMC4608673 · PMID 26474488

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nominally significantP < 0.05actually significant

To account for unmeasured confounders, within each population, we empirically determined the number of gene expression principal components (PCs) to adjust for in order to maximize the number of nominally significant eQTL associations identified ( P < 0.05).

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