Impact of Single Nucleotide Polymorphisms (SNPs) on Immunosuppressive Therapy in Lung Transplantation.

Int J Mol Sci · 2015 · PMC4613195 · PMID 26307985

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an interesting trendno p-value reported

An interesting trend was recorded for the incidence of acute rejection according to NOD2/CARD15 rs2066844 (CT: 27.9%; CC: 12.5%).

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did not reach statistical significanceno p-value reported

The third most relevant SNP in the ABCB1 gene, rs2032582, also showed the expected behaviour according to the literature and our previous data in other series of solid organ transplant patients: the T allele showed a tendency to be associated to increasing blood Tac levels ( Figure 2 B) [ 18 , 19 , 20 ], though here again the data did not reach statistical significance, and in this case none of our patients had the TT genotype.

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