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Cyclin-dependent kinase pathway aberrations in diverse malignancies: clinical and molecular characteristics.

Cell Cycle · 2015 · PMC4614867 · PMID 25695927

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closest p · 1.8× alpha
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showed a trendp = 0.09so close (0.05 < p ≤ 0.1)
In multivariate analysis, PTEN and TP53 aberrations were independently associated with poorer survival (HR = 4.83 and 1.92; P < 0.0001 and p = 0.01); CDK aberrations showed a trend toward worse survival (HR = 1.67; p = 0.09).

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