Darifenacin, in its single pre-planned study of efficacy in patients aged ≥65 years failed to reach statistical significance on its primary outcome but did note that the proportion of people who derived benefit from active treatment were greater than those who received placebo treatment [ 43 ].
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Appropriateness of oral drugs for long-term treatment of lower urinary tract symptoms in older persons: results of a systematic literature review and international consensus validation process (LUTS-FORTA 2014).
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