An update of the Mayo Clinic cohort of patients with adult primary central nervous system vasculitis: description of 163 patients.

Patients with gadolinium-enhanced lesions or meninges on MRI had less risk of death during follow-up than patients who had no such lesions on MRI at presentation (HR, 0.20; 95% CI: 0.06–0.67; P = 0.009), as did patients with ABRA (HR, 0.17; 95% CI: 0.02–1.33); however, only a statistical trend was observed ( P = 0.09).

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We registered a trend toward a reduction in the percentage of patients with bad outcome at last follow-up in the lymphocytic vasculitis group compared with granulomatous and necrotizing groups (0% vs 22.2%), but the difference did not reach statistical significance (=0.096).

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