Correlation of baseline biomarkers with clinical outcomes and response to fulvestrant with vandetanib or placebo in patients with bone predominant metastatic breast cancer: An OCOG ZAMBONEY sub-study.

All tests were two-sided and a p -value of 0.05 or less was considered statistically significant, while a p -value of 0.1 to 0.05 was considered as trending towards significance. 3 Results 3.1 Baseline characteristics Of the 129 women enrolled in Zamboney, 101 had samples available for analysis in the current study.

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Baseline sVEGFR2 was borderline significant as a prognostic marker for PFS, OS and time to first skeletal event.

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