Reductions in diastolic blood pressure (DBP) failed to reach statistical significance and were −0.54 mmHg (−1.15 to 0.07) compared to placebo and −0.50 mmHg (−1.24 to 0.24) compared to active control. 20 Consistent with these observations, clinically significant reductions in blood pressure were observed at week 52 (SBP: −3.6 [0.56] mmHg, P <0.0001; DBP: −1.2 [0.34] mmHg P <0.001) with weekly exenatide.
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Emerging utility of once-weekly exenatide in patients with type 2 diabetes.
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