Associations of prodynorphin sequence variation with alcohol dependence and related traits are phenotype-specific and sex-dependent.

Sci Rep · 2015 · PMC4621530 · PMID 26502829

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only marginally significantno p-value reported

However, the SNP-by-sex interaction for rs2281285 was only marginally significant, indicating that perhaps rs2281285 is not the causal variant, but rather is in LD with a causal variant (or multiple variants) that is also tagged by the PDYN -spanning haplotype.

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