FACT plays a major role in histone dynamics affecting VSG expression site control in Trypanosoma brucei.

Mol Microbiol · 2014 · PMC4625058 · PMID 25266856

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highly significantno p-value reported

At the silent VSG221 ES, knockdown of Spt16 lead to a statistically highly significant decrease in histone H3, in addition to a similar decrease in histone H2A (Fig. 4 A).

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a clear trendno p-value reported

There appeared to be a clear trend, although due to experimental variability these results were not statistically relevant.

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