Gut dendritic cell activation links an altered colonic microbiome to mucosal and systemic T-cell activation in untreated HIV-1 infection.

copri induced the highest fraction of IL-1β + CD1c + mDCs, and this difference was highly significant (p<0.01) when compared to R. bromii ( Figure 7b ).

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In HIV-1-infected subjects, a greater fraction of CD11c + mDCs and HAM56 + macrophages were associated with LPS than with LTA, although this did not reach statistical significance for macrophages ( Figure 5c, d ).

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