We next determined whether fat-digesting lipases, Pnlip (pancreatic lipase) and Pnliprp2 (pancreatic lipase-related protein 2), are downregulated in the pancreas of LMP7 −/− mice and found that the expression of Pnlip and Pnliprp2 was decreased in LMP7 −/− mice, compared to WT mice; however, it did not reach statistical significance.
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Immunoproteasome subunit LMP7 Deficiency Improves Obesity and Metabolic Disorders.
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