Radiosensitization and downregulation of heterogeneous nuclear ribonucleoprotein K (hnRNP K) upon inhibition of mitogen/extracellular signal-regulated kinase (MEK) in malignant melanoma cells.

Oncotarget · 2015 · PMC4627300 · PMID 26136337

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failed to reach statistical significancep = 0.05actually significant

Both hnRNP K siRNA knockdown and MEK inhibition led to the highest fraction of early and late apoptosis under irradiated compared to control conditions, respectively; this result, however, failed to reach statistical significance ( p = 0.05).

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just failed to reach statistical significanceno p-value reported

The results for hnRNP K knockdown in flow cytometry analyses, however, just failed to reach statistical significance and thus, have to be interpreted with caution; possible explanations are the toxic effects of liposomal cell transfection (that could also be observed in the clonogenic viability assays) and the impact of MEK inhibition on other pro-apoptotic pathways unrelated to hnRNP K.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.