Case-control study of glucocorticoid receptor and corticotrophin-releasing hormone receptor gene variants and risk of perinatal depression.

Although not statistically significant, women with perinatal depression showed a trend towards higher frequency of self-reported menstrual irregularity.

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For GR rs41423247 ( Bcl I), although we found no evidence of association with a diagnosis of perinatal depression, there was a highly significant association with the regularity of menstrual cycles.

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