Effects of Intracoronary Administration of Autologous Adipose Tissue-Derived Stem Cells on Acute Myocardial Infarction in a Porcine Model.

Yonsei Med J · 2015 · PMC4630038 · PMID 26446632

Europe PMC DOI

hedged sentences

0.0850

closest p · 1.7× alpha

0.0850

boldest claim

The sentences

marginal significancep =0.085so close (0.05 < p ≤ 0.1)

The infarct area was smaller in the ADSC group with marginal significance (13.9±10.6 cm 2 in the ADSC group vs. 22.7±13.2 cm 2 in the control group; p =0.085) ( Fig. 4 ).

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showed a trendno p-value reported

An interim analysis showed that the intracoronary injection of fhADCs was feasible and safe, and showed a trend toward improved cardiac function and perfusion defects, and reduced myocardial scarring. 4 In conclusion, this study demonstrated that intracoronary administration of cultured ADSCs improved myocardial perfusion defects, reduced LV chamber dilatation and infarct area in a porcine acute MI model.

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