Meanwhile, OPD (0.75 and 1.5 g/kg), OSD (0.15 g/kg) and OSK (0.6, 1.2 and 2.4 g/kg) treatment did not show significant increase of the swimming time in mice (14.73 ± 1.28, 23.96 ± 3.70 and 27.34 ± 5.72 min, respectively) as compared to the control group ( p = 0.897, p = 0.398 and p = 0.268, respectively), but OSD (0.15 g/kg) showed a trend of increasing swimming time, but did not reveal a significant difference ( p = 0.225).
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