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The catalytic A1 domains of cholera toxin and heat-labile enterotoxin are potent DNA adjuvants that evoke mixed Th1/Th17 cellular immune responses.

Hum Vaccin Immunother · 2015 · PMC4635876 · PMID 26042527

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Increases in the anti-gp120 ELISpot responses were also observed but did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.