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A membrane-type-1 matrix metalloproteinase (MT1-MMP)-discoidin domain receptor 1 axis regulates collagen-induced apoptosis in breast cancer cells.

PLoS One · 2015 · PMC4638154 · PMID 25774665

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A similar decrease of DDR1 activation was observed in MT1 cells, however, due to their lower initial level of phosphorylated DDR1, the inhibitory effect of DDR1-IN-1 failed to reach statistical significance ( Fig. 10A , lanes 9 and 11 and Fig. 10E ).

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