Disruption of Ah Receptor Signaling during Mouse Development Leads to Abnormal Cardiac Structure and Function in the Adult.

In agreement with these findings in embryonic hearts, ventricles of adult females exposed in utero to high-dose TCDD showed highly significant changes in the expression of genes in the canonical mitochondrial pathway ( Fig 5A ) and in the oxidative phosphorylation pathway ( Fig 5B ), relative to naïve Ahr +/+ females.

also in 132,142 other papers

No other comparison showed statistical significant, even though exposed wild-type males showed a trend of an increase over control that did not reach significance ( Fig 7A ).

also in 53,322 other papers