HBVEC showed significant reductions in expression of CXCL10 in the presence of the TLR4-blocking agent anti-CD14 in vitro conditions, though decreases in CXCL10 expression in CD34 + -HSPC did not reach statistical significance.
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Heme-Mediated Induction of CXCL10 and Depletion of CD34+ Progenitor Cells Is Toll-Like Receptor 4 Dependent.
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