The enrichment of 91 essential protein subset by Gene Ontology [ 16 ], KEGG [ 17 ] and PharmGKB drug target [ 18 ] categories had shown a significant trend towards membrane proteins, specifically, proteins of plasma membrane and cell periphery ( Fig 3 , S2 Table ).
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Bringing Down Cancer Aircraft: Searching for Essential Hypomutated Proteins in Skin Melanoma.
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