The Protective Role of Interleukin-33 in Myocardial Ischemia and Reperfusion Is Associated with Decreased HMGB1 Expression and Up-Regulation of the P38 MAPK Signaling Pathway.

PLoS One · 2015 · PMC4646496 · PMID 26571038

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closest p · 1.0× alpha

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boldest claim

The sentences

did not reach statistical significanceP>0.05actually significant

Compared with that in the I/R group, the expression level of HMGB1 in anti-ST2+I/R group tended to be higher, but the difference did not reach statistical significance (0.521±0.060, P>0.05).

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an increasing trendno p-value reported

Compared with the I/R group, the group that received anti-ST2 alone did not show significant effects on the serum cTnI (68.1±2.4 pg/ml), LDH (1809.1±48.1 U/L) and CK (4387.7±200.3 U/L) levels (all P>0.05), but there was an increasing trend ( Fig 2B and 2C ).

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