Rapid Modulation of Axon Initial Segment Length Influences Repetitive Spike Firing.

Surprisingly, the features of single spikes fired to a threshold 10-ms current pulse were no different between control and depolarized groups ( Figures 6 C and 6D; Table S1 ), despite a significant depolarization-induced drop in input resistance ( Evans et al., 2013 , Grubb and Burrone, 2010 , O’Leary et al., 2010 ; Table S1 ; Mann-Whitney test, p = 0.044, n = 68) that produced a strong trend toward elevated rheobase in the +15-mM KCl group ( Table S1 ; Mann-Whitney test; p = 0.073, n = 32).

also in 5,725 other papers