Profilin 1 with the amyotrophic lateral sclerosis associated mutation T109M displays unaltered actin binding and does not affect the actin cytoskeleton.

BMC Neurosci · 2015 · PMC4647582 · PMID 26572741

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showed a trendno p-value reported

Solely PFN1 G118V showed a trend towards impairment of this function.

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