Identifying Individual T Cell Receptors of Optimal Avidity for Tumor Antigens.

Front Immunol · 2015 · PMC4649060 · PMID 26635796

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showed a trendno p-value reported

Compared to the native low affinity TCR isolated from the patient’s TIL, referred as DMF4 [ K D 29 μM ( 91 )], with moderate ability to recognize the tumor antigen, Johnson and coworkers ( 92 ) showed a trend of improved clinical efficacy for the DMF5 TCR of higher affinity [ K D 5.6 μM; ( 91 )].

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