Barely Significant
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A comprehensive study of olefin metathesis catalyzed by Ru-based catalysts.

Beilstein J Org Chem · 2015 · PMC4660983 · PMID 26664596

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a clear trendno p-value reported
Indeed, the calculated energy difference between the cis and trans geometries in the coordination intermediates of 2–5 , Δ E of 4th column in Table 2 , follows a clear trend with the bulkiness of the N-substituents, F < Me < CF 3 < t -Bu, Δ E = −8.0 < −5.2 < −3.4 < −2.1 kcal/mol, respectively.

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