Tyrosinase Depletion Prevents the Maturation of Melanosomes in the Mouse Hair Follicle.

PLoS One · 2015 · PMC4664286 · PMID 26619124

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did not reach statistical significanceno p-value reported

While Tyr- shRNA expression did inhibit eumelanin accumulation in the hair of mice with black coats, the observed differences did not reach statistical significance secondary to the intrinsic variation in eumelanin accumulation observed within experimental mice from different litters.

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