Activation of the anti-apoptotic protein expression by stress and glucocorticoids may be significant for preventing the development of stress-induced psychopathology.
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Anti-Apoptotic Protein Bcl-xL Expression in the Midbrain Raphe Region Is Sensitive to Stress and Glucocorticoids.
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Two-way ANOVA revealed a significant effects of stress on both proteins [F(1,29) = 23.435, p < 0.001 for Bcl-xL, and F(1,29) = 10.999, p < 0.01 for TPH], however according the Bonfferoni’s post hoc test, the differences between control and stressed animals did not reach statistical significance for TPH data.