Biochemical analysis of collagen content by the sircol assay showed a trend for increased collagen content in the lungs of rats treated with Si NW at 91 days post-exposure with a significant increase of collagen in the 250 μ g dose of Si NW when compared to control rats ( Figure 8 ).
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Pulmonary Toxicity, Distribution, and Clearance of Intratracheally Instilled Silicon Nanowires in Rats.
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