In a three-dimensional reconstructed human epidermis filaggrin-2 is essential for proper cornification.

Cell Death Dis · 2015 · PMC4669814 · PMID 25695608

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did not reach statistical significanceno p-value reported

Concerning the pyrrolidone carboxylic acid concentration, a similar trend was observed (from 47.66 to 40.68 mmol/ml) but the decrease did not reach statistical significance.

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