Tissue specific expression of extracellular microRNA in human breast cancers and normal human breast tissue in vivo.

In the luteal phase the levels reached borderline significance with a p-value of 0.07 but no changes were seen after tamoxifen therapy, Figure 2 . miRNA-193b, -203, -451, and -452 were unaltered in breast cancers but in normal breast tissue miRNA-193b and miRNA-203 exhibited significantly decreased levels in postmenopausal breast tissue and increased levels in the luteal phase of the menstrual cycle suggesting that hormone exposure may affect their levels, Figure 3 .

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