Presence of Rheumatoid Factor during Chronic HCV Infection Is Associated with Expansion of Mature Activated Memory B-Cells that Are Hypo-Responsive to B-Cell Receptor Stimulation and Persist during the Early Stage of IFN Free Therapy.

PLoS One · 2015 · PMC4674123 · PMID 26649443

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hedged sentence

0.0900

closest p · 1.8× alpha

0.0900

boldest claim

The sentences

showed a trendp = 0.09so close (0.05 < p ≤ 0.1)

HCV RF+ donors bulk B cells also showed a trend towards decreased responsiveness to TLR9 agonist in comparison to HCV RF- donors(p = 0.09).

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