Both mesalazine and TQ showed a tumour reduction from 39% in untreated mice to 21% (p=0.19; RR: 0.53, 95% CI 0.23 to 1.23) and to 31% (p=0.56; RR: 0.79, 95% CI 0.38 to 1.67), respectively, which did not reach statistical significance.
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Mesalazine and thymoquinone attenuate intestinal tumour development in Msh2(loxP/loxP) Villin-Cre mice.
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