nominally significantP < 0.005
Likewise, for Alzheimer’s disease, 14.4% of the top 250 disease SNPs are nominally significant for longevity, which is more than the 8.4% that would be expected by chance (1.7 fold enrichment; P < 0.005).
Likewise, for Alzheimer’s disease, 14.4% of the top 250 disease SNPs are nominally significant for longevity, which is more than the 8.4% that would be expected by chance (1.7 fold enrichment; P < 0.005).
Furthermore, it seems desirable to treat SNPs highly significant for disease differently from SNPs only moderately associated with disease.