There was no detectable difference in RANTES between uninfected and infected DRG tissues, but there was a trend for elevated RANTES in SIV+ DRG with more severe pathology, although this did not reach statistical significance (Fig. 5a ).
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Loss of intraepidermal nerve fiber density during SIV peripheral neuropathy is mediated by monocyte activation and elevated monocyte chemotactic proteins.
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