Similar striatal gene expression profiles in the striatum of the YAC128 and HdhQ150 mouse models of Huntington's disease are not reflected in mutant Huntingtin inclusion prevalence.

A GO term enrichment analysis (Table 1 , Additional file 2 : Table S2) shows that few pathways show an over-representation of significantly differentially expressed genes: only translation (GO:0006412) in the WT 6–12 month striata and cell adhesion (GO:0007155) in the YAC128 6–12 month striata are close to significance.

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Translation does not appear as even nominally significant in the YAC128 data, nor cell adhesion in the WT data (Additional file 2 : Table S2).

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